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TGF-β signaling promotes hepatocarcinogenesis induced by p53 loss
Hepatocellular carcinoma (HCC) results from the accumulation of deregulated tumor suppressor genes and/or oncogenes in hepatocytes. Inactivation of TP53 and inhibition of transforming growth factor-beta (TGF-β) signaling are among the most common molecular events in human liver cancers. Thus, we ass...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237853/ https://ncbi.nlm.nih.gov/pubmed/21898503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24653 |
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