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Role of Aβ-RAGE interaction in oxidative stress and cPLA(2) activation in astrocytes and cerebral endothelial cells

Blood-brain barrier (BBB) dysfunctions have been implicated in the development and progression of Alzheimer's disease. Cerebral endothelial cells (CECs) and astrocytes are the main cell components of the BBB. Although amyloid-β oligomers (Aβ(42)) have been reported to mediate oxidative damage t...

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Bibliografiske detaljer
Main Authors: Askarova, Sholpan, Yang, Xiaoguang, Sheng, Wenwen, Sun, Grace Y., Lee, James C-M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237818/
https://ncbi.nlm.nih.gov/pubmed/21978883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.09.038
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