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Telmisartan ameliorates lipopolysaccharide-induced innate immune response through peroxisome proliferator-activated receptor-γ activation in human monocytes

OBJECTIVE: Angiotensin II type 1 receptor (AT(1)) blockers (ARBs) reduce the bacterial endotoxin lipopolysaccharide (LPS)-induced innate immune response in human circulating monocytes expressing few AT(1). To clarify the mechanisms of anti-inflammatory effects of ARBs with different peroxisome proli...

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Detalhes bibliográficos
Main Authors: Pang, Tao, Benicky, Julius, Wang, Juan, Orecna, Martina, Sanchez-Lemus, Enrique, Saavedra, Juan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237779/
https://ncbi.nlm.nih.gov/pubmed/22124178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e32834dde5f
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