Cortical GAD(67) deficiency results in lower cannabinoid 1 receptor mRNA expression: Implications for schizophrenia

BACKGROUND: Levels of cannabinoid 1 receptor (CB1R) mRNA and protein, which are expressed most heavily in the cholecystokinin class of GABA neurons, are lower in the dorsolateral prefrontal cortex (DLPFC) in schizophrenia, and the magnitude of these differences is strongly correlated with that for g...

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Autores principales: Eggan, Stephen M., Lazarus, Matthew S., Stoyak, Samuel R., Volk, David W., Glausier, Jill R., Huang, Z. Josh, Lewis, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237751/
https://ncbi.nlm.nih.gov/pubmed/22036037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.09.014
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