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Central Role for Interleukin-2 in Type 1 Diabetes

Type 1 diabetes presents clinically with overt hyperglycemia resulting from progressive immune-mediated destruction of pancreatic β-cells and associated metabolic dysfunction. Combined genetic and immunological studies now highlight deficiencies in both the interleukin-2 (IL-2) receptor and its down...

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Autori principali: Hulme, Maigan A., Wasserfall, Clive H., Atkinson, Mark A., Brusko, Todd M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237657/
https://ncbi.nlm.nih.gov/pubmed/22187370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1213
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