Expression of B-RAF V600E in Type II Pneumocytes Causes Abnormalities in Alveolar Formation, Airspace Enlargement and Tumor Formation in Mice

Growth factor induced signaling cascades are key regulatory elements in tissue development, maintenance and regeneration. Perturbations of these cascades have severe consequences, leading to developmental disorders and neoplastic diseases. As a major function in signal transduction, activating mutat...

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Main Authors: Zanucco, Emanuele, Götz, Rudolf, Potapenko, Tamara, Carraretto, Irene, Ceteci, Semra, Ceteci, Fatih, Seeger, Werner, Savai, Rajkumar, Rapp, Ulf R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237599/
https://ncbi.nlm.nih.gov/pubmed/22194995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029093
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