Identification of Novel Androgen-Regulated Pathways and mRNA Isoforms through Genome-Wide Exon-Specific Profiling of the LNCaP Transcriptome

Androgens drive the onset and progression of prostate cancer (PCa) by modulating androgen receptor (AR) transcriptional activity. Although several microarray-based studies have identified androgen-regulated genes, here we identify in-parallel global androgen-dependent changes in both gene and altern...

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Hlavní autoři: Rajan, Prabhakar, Dalgliesh, Caroline, Carling, Phillippa J., Buist, Thomas, Zhang, Chaolin, Grellscheid, Sushma N., Armstrong, Kelly, Stockley, Jacqueline, Simillion, Cedric, Gaughan, Luke, Kalna, Gabriela, Zhang, Michael Q., Robson, Craig N., Leung, Hing Y., Elliott, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237596/
https://ncbi.nlm.nih.gov/pubmed/22194994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029088
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