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Change in antigen specificity of cytotoxic T lymphocytes is associated with the rearrangement and expression of a T-cell receptor beta-chain gene.

Cloned H-Y-specific murine cytotoxic T lymphocytes, which alter antigen specificity in vitro ("aging"), simultaneously exhibit changes in the T-cell antigen receptor beta-chain rearrangements and respective mRNAs expressed. beta-chain cDNA clones were isolated from a library prepared from mRNA of ag...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Epplen, J T, Bartels, F, Becker, A, Nerz, G, Prester, M, Rinaldy, A, Simon, M M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3487087/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4441
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