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Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment.

The gene encoding the beta chain of the human T-cell receptor for antigen is composed of variable (V), diversity (D), joining (J), and constant (C) gene segments which undergo specific rearrangements during T-lymphocyte ontogeny. Southern blot analyses of seven human T-cell tumor lines and normal hu...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Leiden, J M, Dialynas, D P, Duby, A D, Murre, C, Seidman, J, Strominger, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3491297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.9.3207
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