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Paxillin Mediates Sensing of Physical Cues and Regulates Directional Cell Motility by Controlling Lamellipodia Positioning

Physical interactions between cells and the extracellular matrix (ECM) guide directional migration by spatially controlling where cells form focal adhesions (FAs), which in turn regulate the extension of motile processes. Here we show that physical control of directional migration requires the FA sc...

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Bibliografski detalji
Glavni autori: Sero, Julia E., Thodeti, Charles K., Mammoto, Akiko, Bakal, Chris, Thomas, Sheila, Ingber, Donald E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237434/
https://ncbi.nlm.nih.gov/pubmed/22194823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028303
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