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Lack of αvβ5 Integrin Receptor or Its Ligand MFG-E8: Distinct Effects on Retinal Function

BACKGROUND/AIMS: Diurnal phagocytosis of spent photoreceptor outer segment fragments by the retinal pigment epithelium (RPE) is critical for vision. We recently identified an important role for αvβ5 integrin receptors and their ligand Milk fat globule-EGF factor 8 (MFG-E8) in RPE phagocytosis. METHO...

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Autors principals: Nandrot, Emeline F., Finnemann, Silvia C.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237195/
https://ncbi.nlm.nih.gov/pubmed/18421224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000119861
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