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Segregated Regulatory CD39(+) CD4(+) T Cell Function: TGF-β-Producing FoxP3(−) and IL-10-Producing FoxP3(+) Cells Are Interdependent for Protection Against Collagen-Induced Arthritis()

Oral immunization with a Salmonella vaccine vector expressing enterotoxigenic E. coli colonization factor antigen I (CFA/I) can protect against collagen-induced arthritis (CIA) by dampening IL-17 and IFN-γ via enhanced IL-4, IL-10, and TGF-β. To identify the responsible regulatory CD4(+) T cells mak...

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Bibliografiske detaljer
Main Authors: Kochetkova, Irina, Thornburg, Theresa, Callis, Gayle, Pascual, David W.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237119/
https://ncbi.nlm.nih.gov/pubmed/21967895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100530
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