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Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

The possibility of using oligodeoxynucleotides complementary to viral RNA or proviral DNA to inhibit the replication of human T-cell lymphotropic virus type III (HTLV-III) [the etiological agent of acquired immunodeficiency syndrome (AIDS)] in cultured human cells was addressed by studying the assoc...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Zamecnik, P C, Goodchild, J, Taguchi, Y, Sarin, P S
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1986
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3012555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4143
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