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Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

The possibility of using oligodeoxynucleotides complementary to viral RNA or proviral DNA to inhibit the replication of human T-cell lymphotropic virus type III (HTLV-III) [the etiological agent of acquired immunodeficiency syndrome (AIDS)] in cultured human cells was addressed by studying the assoc...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zamecnik, P C, Goodchild, J, Taguchi, Y, Sarin, P S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3012555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.12.4143
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