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Concerted but Noncooperative Activation of Nucleotide and Actuator Domains of the Ca-ATPase Upon Calcium Binding

Calcium-dependent domain movements of the actuator (A) and nucleotide (N) domains of the SERCA2a isoform of the Ca-ATPase were assessed using constructs containing engineered tetracysteine binding motifs, which were expressed in insect High-Five cells and subsequently labeled with the biarsenical fl...

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Detalhes bibliográficos
Main Authors: Chen, Baowei, Mahaney, James E., Mayer, M. Uljana, Bigelow, Diana J., Squier, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236681/
https://ncbi.nlm.nih.gov/pubmed/18956892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8014289
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