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Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling

INTRODUCTION: Natriuretic peptides modulate cardiac hypertrophy and are potential therapeutic options for patients with heart failure. Caveolae, microdomains in the plasma membrane that contain caveolin proteins and natriuretic peptide receptors, have been implicated in cardiac hypertrophy and natri...

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Main Authors: Horikawa, Yousuke T., Panneerselvam, Mathivadhani, Kawaraguchi, Yoshitaka, Tsutsumi, Yasuo M., Ali, Sameh S., Balijepalli, Ravi C., Murray, Fiona, Head, Brian P., Niesman, Ingrid R., Rieg, Timo, Vallon, Volker, Insel, Paul A., Patel, Hemal H., Roth, David M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236642/
https://ncbi.nlm.nih.gov/pubmed/21616289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.12.032
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