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Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling

INTRODUCTION: Natriuretic peptides modulate cardiac hypertrophy and are potential therapeutic options for patients with heart failure. Caveolae, microdomains in the plasma membrane that contain caveolin proteins and natriuretic peptide receptors, have been implicated in cardiac hypertrophy and natri...

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Bibliografiske detaljer
Main Authors: Horikawa, Yousuke T., Panneerselvam, Mathivadhani, Kawaraguchi, Yoshitaka, Tsutsumi, Yasuo M., Ali, Sameh S., Balijepalli, Ravi C., Murray, Fiona, Head, Brian P., Niesman, Ingrid R., Rieg, Timo, Vallon, Volker, Insel, Paul A., Patel, Hemal H., Roth, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236642/
https://ncbi.nlm.nih.gov/pubmed/21616289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.12.032
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