Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

The detailed protein composition of the paired helical filaments (PHF) that accumulate in human neurons in aging and Alzheimer disease is unknown. However, the identity of certain components has been surmised by using immunocytochemical techniques. Whereas PHF share epitopes with neurofilament prote...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kosik, K S, Joachim, C L, Selkoe, D J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323662/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2424016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.4044
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