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Sphingosine-1-phosphate induces development of functionally mature chymase-expressing human mast cells from hematopoietic progenitors

Mast cells (MCs) play a critical role in both acute and chronic inflammation and mature in peripheral tissues from bone marrow-derived progenitors that circulate in the blood as immature precursors. MCs developed from cord blood-derived progenitors cultured with stem cell factor (SCF) alone express...

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Autores principales: Price, Megan M., Kapitonov, Dmitri, Allegood, Jeremy, Milstien, Sheldon, Oskeritzian, Carole A., Spiegel, Sarah
Formato: Artigo
Lenguaje:Inglês
Publicado: The Federation of American Societies for Experimental Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236593/
https://ncbi.nlm.nih.gov/pubmed/19535686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-128900
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