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Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions
Sphingosine-1-phosphate (S1P) is now emerging as a potent lipid mediator produced by mast cells that contributes to inflammatory and allergic responses. In contrast to its weak effect on degranulation of murine mast cells, S1P potently induced degranulation of the human LAD2 mast-cell line and cord...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2971746/ https://ncbi.nlm.nih.gov/pubmed/18178871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115451 |
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