Neuroprotective effects of Tacrolimus (FK-506) and Cyclosporin (CsA) in oxidative injury

The detrimental effects of hypoxic damage to central nervous system lead to energy depletion, free radical formation, lipid peroxidation (LPO), and increased calcium. We hypothesized that in vitro tacrolimus (FK-506) and cyclosporine A (CsA) could be protective against hypoxic damage in spinal cord....

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Bibliographic Details
Main Authors: Yousuf, Seema, Atif, Fahim, Kesherwani, Varun, Agrawal, Sandeep Kumar
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Inc 2011
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236540/
https://ncbi.nlm.nih.gov/pubmed/22399088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.16
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