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Osteoblastic and Vascular Endothelial Niches, Their Control on Normal Hematopoietic Stem Cells, and Their Consequences on the Development of Leukemia
Stem cell self-renewal is regulated by intrinsic mechanisms and extrinsic signals mediated via specialized microenvironments called “niches.” The best-characterized stem cell is the hematopoietic stem cell (HSC). Self-renewal and differentiation ability of HSC are regulated by two major elements: en...
সংরক্ষণ করুন:
প্রধান লেখক: | , , |
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বিন্যাস: | Artigo |
ভাষা: | Inglês |
প্রকাশিত: |
SAGE-Hindawi Access to Research
2011
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বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3236318/ https://ncbi.nlm.nih.gov/pubmed/22190963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/375857 |
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