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Hybrid metabolic flux analysis: combining stoichiometric and statistical constraints to model the formation of complex recombinant products
BACKGROUND: Stoichiometric models constitute the basic framework for fluxome quantification in the realm of metabolic engineering. A recurrent bottleneck, however, is the establishment of consistent stoichiometric models for the synthesis of recombinant proteins or viruses. Although optimization alg...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3236310/ https://ncbi.nlm.nih.gov/pubmed/21352531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-34 |
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