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Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene.

The survival of UV-irradiated mammalian cells is not necessarily correlated with their overall capacity to carry out DNA repair. Human cells typically remove 80% of the pyrimidine dimers produced by a UV dose of 5 J/m2 within 24 hr. In contrast, a Chinese hamster ovary (CHO) cell line survives UV ir...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bohr, V A, Okumoto, D S, Hanawalt, P C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3459159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3830
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