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Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice
Iron is an essential component of heme and hemoglobin, and therefore restriction of iron availability directly limits erythropoiesis. In the present study, we report a defect in iron absorption that results in iron-deficiency anemia, as revealed by an N-ethyl-N-nitrosourea–induced mouse phenotype ca...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3236123/ https://ncbi.nlm.nih.gov/pubmed/21976678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-350082 |
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