Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis

The aim of the present investigation was to elucidate the cellular mechanisms whereby Tanshinone IIA (Tan IIA) leads to cell cycle arrest and apoptosis in vitro in keratinocytes, the target cells in psoriasis. Tan IIA inhibited proliferation of mouse keratinocytes in a dose- and time-dependent manne...

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Hlavní autoři: Li, Fu-Lun, Xu, Rong, Zeng, Qing-chun, Li, Xin, Chen, Jie, Wang, Yi-Fei, Fan, Bin, Geng, Lin, Li, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236062/
https://ncbi.nlm.nih.gov/pubmed/22203883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/927658
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