Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis

The aim of the present investigation was to elucidate the cellular mechanisms whereby Tanshinone IIA (Tan IIA) leads to cell cycle arrest and apoptosis in vitro in keratinocytes, the target cells in psoriasis. Tan IIA inhibited proliferation of mouse keratinocytes in a dose- and time-dependent manne...

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Main Authors: Li, Fu-Lun, Xu, Rong, Zeng, Qing-chun, Li, Xin, Chen, Jie, Wang, Yi-Fei, Fan, Bin, Geng, Lin, Li, Bin
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236062/
https://ncbi.nlm.nih.gov/pubmed/22203883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/927658
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