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Lipofuscin Hypothesis of Alzheimer's Disease

The primary culprit responsible for Alzheimer's disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the formation of extracellular Aβ deposits is the absolute h...

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Bibliografski detalji
Glavni autori: Giaccone, Giorgio, Orsi, Laura, Cupidi, Chiara, Tagliavini, Fabrizio
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235942/
https://ncbi.nlm.nih.gov/pubmed/22545040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329544
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