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Lipofuscin Hypothesis of Alzheimer's Disease

The primary culprit responsible for Alzheimer's disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the formation of extracellular Aβ deposits is the absolute h...

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Autors principals: Giaccone, Giorgio, Orsi, Laura, Cupidi, Chiara, Tagliavini, Fabrizio
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235942/
https://ncbi.nlm.nih.gov/pubmed/22545040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329544
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