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Lipofuscin Hypothesis of Alzheimer's Disease

The primary culprit responsible for Alzheimer's disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the formation of extracellular Aβ deposits is the absolute h...

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Detalhes bibliográficos
Main Authors: Giaccone, Giorgio, Orsi, Laura, Cupidi, Chiara, Tagliavini, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235942/
https://ncbi.nlm.nih.gov/pubmed/22545040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329544
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