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Lipofuscin Hypothesis of Alzheimer's Disease

The primary culprit responsible for Alzheimer's disease (AD) remains unknown. Aβ protein has been identified as the main component of amyloid of senile plaques, the hallmark lesion of AD, but it is not definitively established whether the formation of extracellular Aβ deposits is the absolute h...

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Dettagli Bibliografici
Autori principali: Giaccone, Giorgio, Orsi, Laura, Cupidi, Chiara, Tagliavini, Fabrizio
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235942/
https://ncbi.nlm.nih.gov/pubmed/22545040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329544
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