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A Fluorescence Displacement Assay for Antidepressant Drug Discovery Based on Ligand Conjugated Quantum Dots

[Image: see text] The serotonin (5-hydroxytryptamine, 5-HT) transporter (SERT) protein plays a central role in terminating 5-HT neurotransmission and is the most important therapeutic target for the treatment of major depression and anxiety disorders. We report an innovative, versatile, and target-s...

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Détails bibliographiques
Auteurs principaux: Chang, Jerry C., Tomlinson, Ian D., Warnement, Michael R., Iwamoto, Hideki, DeFelice, Louis J., Blakely, Randy D., Rosenthal, Sandra J.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235909/
https://ncbi.nlm.nih.gov/pubmed/21970724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja204301g
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