Single Molecule Analysis of Serotonin Transporter Regulation Using Antagonist-Conjugated Quantum Dots Reveals Restricted, p38 MAPK-Dependent Mobilization Underlying Uptake Activation

The presynaptic serotonin (5-HT) transporter (SERT) is targeted by widely prescribed antidepressant medications. Altered SERT expression or regulation has been implicated in multiple neuropsychiatric disorders, including anxiety, depression and autism. Here, we implement a generalizable strategy tha...

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Detalhes bibliográficos
Main Authors: Chang, Jerry C., Tomlinson, Ian D., Warnement, Michael R., Ustione, Alessandro, Carneiro, Ana M. D., Piston, David W., Blakely, Randy D., Rosenthal, Sandra J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426861/
https://ncbi.nlm.nih.gov/pubmed/22745492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0048-12.2012
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