Somatic mutation of Fibroblast Growth Factor Receptor-3 (FGFR3) defines a distinct morphologic subtype of high-grade urothelial carcinoma

FGFR3 mutations are common in low grade urothelial carcinoma and represent a potential therapeutic target in this disease. Their incidence and functional role in high grade urothelial carcinoma (HGUC), which displays an increased propensity for recurrence and muscularis propria invasion, is less wel...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Al-Ahmadie, Hikmat A., Iyer, Gopa, Janakiraman, Manickam, Lin, Oscar, Heguy, Adriana, Tickoo, Satish K., Fine, Samson W., Gopalan, Anuradha, Chen, Ying-bei, Balar, Arjun, Riches, Jamie, Bochner, Bernard, Dalbagni, Guido, Bajorin, Dean F., Reuter, Victor E., Milowsky, Matthew I., Solit, David B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235805/
https://ncbi.nlm.nih.gov/pubmed/21547910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2892
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi