Somatic mutation of Fibroblast Growth Factor Receptor-3 (FGFR3) defines a distinct morphologic subtype of high-grade urothelial carcinoma

FGFR3 mutations are common in low grade urothelial carcinoma and represent a potential therapeutic target in this disease. Their incidence and functional role in high grade urothelial carcinoma (HGUC), which displays an increased propensity for recurrence and muscularis propria invasion, is less wel...

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Detalhes bibliográficos
Main Authors: Al-Ahmadie, Hikmat A., Iyer, Gopa, Janakiraman, Manickam, Lin, Oscar, Heguy, Adriana, Tickoo, Satish K., Fine, Samson W., Gopalan, Anuradha, Chen, Ying-bei, Balar, Arjun, Riches, Jamie, Bochner, Bernard, Dalbagni, Guido, Bajorin, Dean F., Reuter, Victor E., Milowsky, Matthew I., Solit, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235805/
https://ncbi.nlm.nih.gov/pubmed/21547910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2892
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