Somatic mutation of Fibroblast Growth Factor Receptor-3 (FGFR3) defines a distinct morphologic subtype of high-grade urothelial carcinoma

FGFR3 mutations are common in low grade urothelial carcinoma and represent a potential therapeutic target in this disease. Their incidence and functional role in high grade urothelial carcinoma (HGUC), which displays an increased propensity for recurrence and muscularis propria invasion, is less wel...

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Detaylı Bibliyografya
Asıl Yazarlar: Al-Ahmadie, Hikmat A., Iyer, Gopa, Janakiraman, Manickam, Lin, Oscar, Heguy, Adriana, Tickoo, Satish K., Fine, Samson W., Gopalan, Anuradha, Chen, Ying-bei, Balar, Arjun, Riches, Jamie, Bochner, Bernard, Dalbagni, Guido, Bajorin, Dean F., Reuter, Victor E., Milowsky, Matthew I., Solit, David B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235805/
https://ncbi.nlm.nih.gov/pubmed/21547910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2892
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