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Practical Synthesis of 2-Keto-3-deoxy-D-glycero-D-galactononulosonic acid (KDN)

[Image: see text] Reaction of propargylmagnesium bromide with 2,3;5,6-di-O-isopropylidene-D-mannonolactone followed by highly stereoselective reduction of the so-formed lactol with sodium borohydride gives a syn-diol from which practical syntheses of 2-keto-3-deoxy-D-glycero-D-galactononulosonic aci...

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Autores principales: Crich, David, Navuluri, Chandrasekhar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235743/
https://ncbi.nlm.nih.gov/pubmed/22070804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol202773t
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