Functional and Epigenetic Analyses of In Vitro-generated and In Vivo-derived Interleukin-21-Producing Follicular T helper-like cells

Follicular T helper cells (Tfh) provide critical help to B cells for germinal center (GC) formation. Mutations affecting SLAM-associated Protein (SAP) prevent GC formation due to defective T-B cell interactions, yet effects on Tfh cell differentiation remain unclear. We describe the in vitro differe...

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Autors principals: Lu, Kristina T., Kanno, Yuka, Cannons, Jennifer L., Handon, Robin, Bible, Paul, Elkahloun, Abdel G., Anderson, Stacie M., Wei, Lai, Sun, Hongwei, O’Shea, John J., Schwartzberg, Pamela L.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235706/
https://ncbi.nlm.nih.gov/pubmed/22018472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.07.015
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