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Catalytic Asymmetric [4 + 2] Additions with Aliphatic Nitroalkenes

We describe an unprecedented cycloaddition reaction of 2-pyrones with aliphatic nitroalkenes catalyzed by a new bifunctional cinchona alkaloid-derived catalyst bearing a bulky TIPS-ether at the 9-position. The [2.2.2] bicyclic adducts were obtained in good yield with excellent diastereo- and enantio...

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Hlavní autoři: Bartelson, Keith J., Singh, Ravi P., Foxman, Bruce M., Deng, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235653/
https://ncbi.nlm.nih.gov/pubmed/22174973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1sc00326g
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