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Catalytic Asymmetric Intermolecular Stetter Reaction of Enals with Nitroalkenes: Enhancement of Catalytic Efficiency Through Bifunctional Additives

An asymmetric intermolecular Stetter reaction of enals with nitroalkenes, catalyzed by chiral N-heterocyclic carbenes, has been developed. Reaction rate and efficiency are profoundly impacted by the presence of catechol. The reaction proceeds with high selectivities affording good yields of the Stet...

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Detalhes bibliográficos
Main Authors: DiRocco, Daniel A., Rovis, Tomislav
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147302/
https://ncbi.nlm.nih.gov/pubmed/21678918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja203810b
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