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Human intestinal acyl-CoA synthetase 5 is sensitive to the inhibitor triacsin C

AIM: To investigate whether human acyl-CoA synthetase 5 (ACSL5) is sensitive to the ACSL inhibitor triacsin C. METHODS: The ACSL isoforms ACSL1 and ACSL5 from rat as well as human ACSL5 were cloned and recombinantly expressed as 6xHis-tagged enzymes. Ni(2+)-affinity purified recombinant enzymes were...

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Bibliografiska uppgifter
Huvudupphovsmän: Kaemmerer, Elke, Peuscher, Anne, Reinartz, Andrea, Liedtke, Christian, Weiskirchen, Ralf, Kopitz, Jürgen, Gassler, Nikolaus
Materialtyp: Artigo
Språk:Inglês
Publicerad: Baishideng Publishing Group Co., Limited 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235631/
https://ncbi.nlm.nih.gov/pubmed/22171129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i44.4883
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