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Chemically induced mutagenesis in a shuttle vector with a low-background mutant frequency.
We have developed a recombinant DNA shuttle vector that permits the molecular analysis of mutations induced in human cells by chemical or physical mutagens. The vector is able to replicate as a plasmid in Escherichia coli and in Epstein-Barr virus (EBV)-transformed human lymphoblastoid cell lines an...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323522/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3010297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.10.3402 |
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