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Erroneous attribution of relevant transcription factor binding sites despite successful prediction of cis-regulatory modules

BACKGROUND: Cis-regulatory modules are bound by transcription factors to regulate gene expression. Characterizing these DNA sequences is central to understanding gene regulatory networks and gaining insight into mechanisms of transcriptional regulation, but genome-scale regulatory module discovery r...

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Détails bibliographiques
Auteurs principaux: Halfon, Marc S, Zhu, Qianqian, Brennan, Elizabeth R, Zhou, Yiyun
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235160/
https://ncbi.nlm.nih.gov/pubmed/22115527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-578
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