Streamlining Homogeneous Glycoprotein Production for Biophysical and Structural Applications by Targeted Cell Line Development

Studying the biophysical characteristics of glycosylated proteins and solving their three-dimensional structures requires homogeneous recombinant protein of high quality.We introduce here a new approach to produce glycoproteins in homogenous form with the well-established, glycosylation mutant CHO L...

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Main Authors: Wilke, Sonja, Groebe, Lothar, Maffenbeier, Vitali, Jäger, Volker, Gossen, Manfred, Josewski, Jörn, Duda, Agathe, Polle, Lilia, Owens, Raymond J., Wirth, Dagmar, Heinz, Dirk W., van den Heuvel, Joop, Büssow, Konrad
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235087/
https://ncbi.nlm.nih.gov/pubmed/22174749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027829
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