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Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila

Spinocerebellar ataxia 3 (SCA3) is the most common autosomal dominant ataxia. The disease is caused by an expansion of a CAG-trinucelotide repeat region within the coding sequence of the ATXN3 gene, and this results in an expanded polyglutamine (polyQ) tract within the Ataxin-3 protein. The polyQ ex...

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Detalhes bibliográficos
Main Authors: McGurk, Leeanne, Bonini, Nancy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235011/
https://ncbi.nlm.nih.gov/pubmed/21949352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr439
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