Curcumin Differentially Regulates Endoplasmic Reticulum Stress through Transcriptional Corepressor SMILE (Small Heterodimer Partner-interacting Leucine Zipper Protein)-mediated Inhibition of CREBH (cAMP Responsive Element-binding Protein H)

Curcumin (diferuloylmethane), a major active component of turmeric (Curcuma longa), is a natural polyphenolic compound. Herein the effect of curcumin on endoplasmic reticulum (ER) stress responsive gene expression was investigated. We report that curcumin induces transcriptional corepressor small he...

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Detalhes bibliográficos
Main Authors: Misra, Jagannath, Chanda, Dipanjan, Kim, Don-kyu, Li, Tiangang, Koo, Seung-Hoi, Back, Sung-Hoon, Chiang, John Y. L., Choi, Hueng-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234973/
https://ncbi.nlm.nih.gov/pubmed/21994947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.274514
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