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Hepatitis C Virus Core Protein Decreases Lipid Droplet Turnover: A MECHANISM FOR CORE-INDUCED STEATOSIS

Steatosis is a frequent complication of hepatitis C virus infection. In mice, this condition is recapitulated by the expression of a single viral protein, the nucleocapsid core. Core localizes to the surface of lipid droplets (LDs) in infected liver cells through a process dependent on host diacylgl...

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Detalhes bibliográficos
Main Authors: Harris, Charles, Herker, Eva, Farese, Robert V., Ott, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234948/
https://ncbi.nlm.nih.gov/pubmed/21984835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.285148
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