Capturing a Fusion Intermediate of Influenza Hemagglutinin with a Cholesterol-conjugated Peptide, a New Antiviral Strategy for Influenza Virus

We previously described fusion-inhibitory peptides that are targeted to the cell membrane by cholesterol conjugation and potently inhibit enveloped viruses that fuse at the cell surface, including HIV, parainfluenza, and henipaviruses. However, for viruses that fuse inside of intracellular compartme...

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Bibliographic Details
Main Authors: Lee, Kelly K., Pessi, Antonello, Gui, Long, Santoprete, Alessia, Talekar, Aparna, Moscona, Anne, Porotto, Matteo
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234914/
https://ncbi.nlm.nih.gov/pubmed/21994935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254243
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