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Capturing a Fusion Intermediate of Influenza Hemagglutinin with a Cholesterol-conjugated Peptide, a New Antiviral Strategy for Influenza Virus

We previously described fusion-inhibitory peptides that are targeted to the cell membrane by cholesterol conjugation and potently inhibit enveloped viruses that fuse at the cell surface, including HIV, parainfluenza, and henipaviruses. However, for viruses that fuse inside of intracellular compartme...

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Detalhes bibliográficos
Main Authors: Lee, Kelly K., Pessi, Antonello, Gui, Long, Santoprete, Alessia, Talekar, Aparna, Moscona, Anne, Porotto, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234914/
https://ncbi.nlm.nih.gov/pubmed/21994935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254243
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