Genetic Ablation of the Aryl Hydrocarbon Receptor Causes Cigarette Smoke-induced Mitochondrial Dysfunction and Apoptosis

Cigarette smoke is the primary risk factor for chronic obstructive pulmonary disease (COPD). Alterations in the balance between apoptosis and proliferation are involved in the etiology of COPD. Fibroblasts and epithelial cells are sensitive to the oxidative properties of cigarette smoke, and whose l...

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Bibliographische Detailangaben
Hauptverfasser: Rico de Souza, Angela, Zago, Michela, Pollock, Stephen J., Sime, Patricia J., Phipps, Richard P., Baglole, Carolyn J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234839/
https://ncbi.nlm.nih.gov/pubmed/21984831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258764
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