Francisella tularensis Reveals a Disparity between Human and Mouse NLRP3 Inflammasome Activation

Pathogen-triggered activation of the inflammasome complex leading to caspase-1 activation and IL-1β production involves similar sensor proteins between mouse and human. However, the specific sensors used may differ between infectious agents and host species. In mice, Francisella infection leads to s...

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Bibliographic Details
Main Authors: Atianand, Maninjay K., Duffy, Ellen B., Shah, Aaloki, Kar, Supriya, Malik, Meenakshi, Harton, Jonathan A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234728/
https://ncbi.nlm.nih.gov/pubmed/21930705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244079
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