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Francisella tularensis Reveals a Disparity between Human and Mouse NLRP3 Inflammasome Activation
Pathogen-triggered activation of the inflammasome complex leading to caspase-1 activation and IL-1β production involves similar sensor proteins between mouse and human. However, the specific sensors used may differ between infectious agents and host species. In mice, Francisella infection leads to s...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234728/ https://ncbi.nlm.nih.gov/pubmed/21930705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244079 |
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