Promoting Effects of Streptozotocin-induced Diabetes on Induction of Hepatic Preneoplastic Lesions by Diethylnitrosamine in Rats

The effects of streptozotocin (STZ)-induced diabetes on induction of hepatic preneoplastic lesions by diethylnitrosamine (DEN) were investigated in male Fischer rats. A single dose of STZ was injected intravenously either 2 weeks before or after initiation with DEN. The blood glucose levels were sig...

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Bibliographic Details
Main Authors: Ichikawa, Kazuhito, Tagawa, Yoshiaki, Kawai, Masaomi, Asamoto, Makoto, Shirai, Tomoyuki
Format: Artigo
Language:Inglês
Published: The Japanese Society of Toxicologic Pathology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234616/
https://ncbi.nlm.nih.gov/pubmed/22272023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.23.125
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