In Vitro Downregulation of Matrix Metalloproteinase-9 in Rat Glial Cells by CCR5 Antagonist Maraviroc: Therapeutic Implication for HIV Brain Infection

BACKGROUND: Matrix metalloproteinases (MMPs) released by glial cells are important mediators of neuroinflammation and neurologic damage in HIV infection. The use of antiretroviral drugs able to combat the detrimental effect of chronic inflammation and target the exaggerated MMP activity might repres...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gramegna, Pasqua, Latronico, Tiziana, Branà, Maria Teresa, Di Bari, Gaetano, Mengoni, Fabio, Belvisi, Valeria, Mascellino, Maria T., Lichtner, Miriam, Vullo, Vincenzo, Mastroianni, Claudio M., Liuzzi, Grazia M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234279/
https://ncbi.nlm.nih.gov/pubmed/22174822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028499
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