Role of Collagens and Perlecan in Microvascular Stability: Exploring the Mechanism of Capillary Vessel Damage by Snake Venom Metalloproteinases

Hemorrhage is a clinically important manifestation of viperid snakebite envenomings, and is induced by snake venom metalloproteinases (SVMPs). Hemorrhagic and non-hemorrhagic SVMPs hydrolyze some basement membrane (BM) and associated extracellular matrix (ECM) proteins. Nevertheless, only hemorrhagi...

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Main Authors: Escalante, Teresa, Ortiz, Natalia, Rucavado, Alexandra, Sanchez, Eladio F., Richardson, Michael, Fox, Jay W., Gutiérrez, José María
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234262/
https://ncbi.nlm.nih.gov/pubmed/22174764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028017
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